Spermine and the Next Frontier: Harnessing Polyamine-Driv...
2025-10-19
Explore how spermine, an endogenous polyamine, is redefining the landscape of cellular metabolism and ion channel regulation. This thought-leadership article provides mechanistic insight into spermine’s role as a physiological blocker of inward rectifier potassium channels, contextualizes recent advances in membrane fusion research, and offers strategic guidance for translational researchers seeking to leverage spermine in next-generation neurophysiology and cell biology studies.